Prenatal air pollution exposure and growth: The role of placental mtDNA content
نویسندگان
چکیده
Background and aims In recent years, evidence has shown that prenatal trafficrelated air pollution exposure influences fetal growth. Changes in mitochondrial DNA (mtDNA) content may represent a biologically relevant endpoint on the mechanisms underlying the association between air pollution and fetal growth restrictions. In this study, we aimed to assess the role of placental mtDNA content on the association of prenatal NO2 exposure with fetal growth assessed by ultrasound measurements.
منابع مشابه
Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts
BACKGROUND Mitochondria are sensitive to environmental toxicants due to their lack of repair capacity. Changes in mitochondrial DNA (mtDNA) content may represent a biologically relevant intermediate outcome in mechanisms linking air pollution and fetal growth restriction. OBJECTIVE We investigated whether placental mtDNA content is a possible mediator of the association between prenatal nitro...
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عنوان ژورنال:
دوره 73 شماره
صفحات -
تاریخ انتشار 2015